|
Antiarrhythmic Agents
|
|
Amiodarone
|
Dog |
10-20 mg/kg SID (PO) for 7-10 days (loading dose), then 3-15 mg/kg SID |
Pulmonary fibrosis, GI, hepatitis, leukopenias, bradycardia |
| Cat |
Unknown |
|
Aprindine
|
Dog |
0.5-2.0 mg/kg (IV); TID (PO)
|
GI, seizure, hepatitis |
| Cat |
Unknown
|
|
Digoxin
|
Dog |
0.22 mg/m2 BID (PO) |
GI, depression, anorexia, bradycardia, arrhythmias |
| Cat |
1/4 of 0.125 mg (PO) q 48h - SID |
|
Flecainide
|
Dog |
1-5 mg/kg BID-TID (PO); Dr. Fox suggests 3-10 mg/kg TID (PO) 1-2 mg/kg (IV) slowly
|
GI, weakness, confusion, depression |
| Cat |
Unknown
|
|
Lidocaine
|
Dog |
2-4 mg/kg slow (IV), repeat q 10 min. to maximum of 8 mg/kg; 25-75 ug/kg/min (CRI) |
Seizures, CNS excitation (seizures), GI, arrhythmias, hypotension |
| Cat |
0.25-1.0 mg/kg slow (IV) over 5 minutes |
|
Mexiletine
|
Dog |
2-5 mg/kg BID-TID (PO) (oral lidocaine) Dr. Fox suggests 5-10 mg/kg BID-TID (PO) |
As for lidocaine |
| Cat |
unknown
|
|
Phenytoin
|
Dog |
5-10 mg/kg (IV) slow; 35 mg/kg TID (PO) |
Depression, seizures |
| Cat |
None |
|
Procainamide
|
Dog |
6-8 mg/kg (IV) over 5 min; 25-40 ug/kg/min (CRI); 8-20 mg/kg q 4-6 hr (IM), TID (PO) (slow release formulation)
|
Weakness, hypotension, negative inotropic, GI, bradycardia |
| Cat |
8-20 mg/kg TID (PO) |
|
Propafenone
|
Dog |
3-6 mg/kg q8 hrs |
Transient arrhythmia & hypotension |
| Cat |
unknown |
|
Quinidine
|
Dog |
gluconate 6-20 mg/kg QID (IM); Extentab (sulfate) 6-16 mg/kg TID (PO); Quinaglute, Cardioquin 8-20 mg/kg TID-QID (PO); 5-10 mg/kg (IV)
|
As per procainamide, interacts with digoxin |
| Cat |
Sulfate 5.5-11.0 mg/kg TID (PO)
|
|
Sotalol
|
Dog |
0.5-2 mg/kg BID (PO) |
As per beta-blockers |
| Cat |
Unknown |
|
Tocainide
|
Dog |
5-10 mg/kg TID-QID (PO); (oral lidocaine) Dr. Hamlin suggests 25 mg/kg QID (PO) |
As for lidocaine |
| Cat |
unknown
|
